高压共轨喷油器喷射特性实验与仿真

采用实验与数值模拟相结合的方法,进行了不同控制参数:共轨压力、喷油脉宽条件下高压共轨喷油器的喷射特性研究。通过实验数据总结了电磁式喷油器喷油量、喷油率、针阀开启延迟与关闭延迟、喷油持续期等喷射特性。利用AMESim软件建立的高压共轨燃油系统模型进行仿真计算,与实测喷油器喷油率结果进行了对比验证,分析了共轨系统喷射过程中喷油器内液力过程和针阀运动特性,得到了高压共轨喷油器喷射特性随共轨压力和喷油脉宽的变化机理和规律。     

基于Moldflow的注塑成型充填过程的数值研究

由于产品的注塑成型过程非常复杂,而充填过程的模拟计算机软件在预测型腔的流动行为方面已经比较准确。采用Moldflow充模模块,对手机外壳的充模流动过程进行了动态模拟,分析和讨论了影响产品质量的主要原因和问题。     

注塑成型工艺的混合智能优化

注塑成型过程系统动力学的不确定性和复杂性,限制了传统优化技术的运用。将智能优化技术引入注塑成型工艺优化,以成型过程的主要工艺参数为设计变量,利用BP网络获得工艺参数对各质量指标的近似计算关系式,以各质量指标的模糊综合评价函数为遗传算法的适应度函数,建立了解决多因素作用和多指标约束的注塑成型工艺的混合智能优化模型。通过对比实例的正交仿真试验结果,验证了该模型能快速、自动地实现非线性和不确定系统的优化求解。     

柴油机高压喷射系统发展及应用现状研究

介绍了柴油机高压喷油系统发展概况，对常见几种高压喷油系统进行了比较，并就高压共轨系统的基本原理、应用现状及发展前景作了阐述。     

车用柴油机缩口型燃烧系统参数优化试验研究

在小型增压直喷式柴油机上采用缩口排放型燃烧室，对其喷射系统参数进行匹配试验研究。试验结果表明，在不影响柴油机性能的前提下，通过喷射系统参数的优化匹配，有效地改善了排放特性。     

高压共轨式柴油机多次喷射的数值模拟

构建了高压共轨喷射系统的计算模型，并在试验台架上进行了试验验证。对喷油器的电磁、液力和机械特性进行了模拟计算，分析了多次喷射的机理，确定了多次喷射的喷油定时和喷油脉冲间隔。     

Outbreak of sarcoptic mange in alpacas (Vicugna pacos) and control with repeated subcutaneous ivermectin injections

An outbreak of sarcoptic mange was investigated in an alpaca herd. Clinical disease occurred 2 months after the introduction of four alpacas with dry seborrhoeic skin lesions, the cause of which was not investigated. Initially a group of females was affected, despite repeated topical treatment with ivermectin at a dose of 0.5 mg/kg bodyweight. One female died and post-mortem examination indicated sarcoptic mange as the cause of death. Infection with Sarcoptes scabiei was also demonstrated on microscopic examination of skin scrapes taken from clinically affected cohorts. Later in the outbreak, a separate group of male alpacas was also affected. Treatment using subcutaneous ivermectin injections at a dose of 0.2 mg/kg, administered at 14-day intervals, was evaluated. During this course of treatment, another female died. A successful response in the other alpacas was eventually reached following 12 treatments of the female group and 8 treatments of the male group.     

Breed-related plasma disposition of ivermectin following subcutaneous administration in Kilis and Damascus goats

Many factors related with drug and animals affect the plasma disposition of endectocides including ivermectin (IVM). The aim of the present study was to investigate the breed differences in pharmacokinetics of IVM in goats following subcutaneous administration. Two different goat breeds (Kilis and Damascus goats) were allocated into two treatment groups with respect to breed. The injectable formulation of IVM was administered subcutaneously at a dose rate of 0.2 mg/kg bodyweight. Blood samples were collected before treatment and at various times between 1 h and 40 days after treatment and the plasma samples were analysed by high performance liquid chromatography (HPLC) using fluorescence detection. The results indicated that the plasma disposition of IVM was substantially affected by breed differences following subcutaneous administration in goats. The last detectable plasma concentration (t_last) of IVM was significantly later in Kilis goats (38.33 days) compared with Damascus goats (22.50 days). Although, there were no significant differences on C_max (10.83 ng/ml vs. 10.15 ng/ml) and t_max (2.75 days vs. 2.33 days) values; the area under the concentration–time curve-AUC (110.26 ng.d/ml vs. 73.38 ng.d/ml) the terminal half-life-t_1/2λz (5.65 days vs. 3.81 days) and the mean plasma residence time-MRT (9.31 days vs. 6.35 days) were significantly different in Kilis goats compared with Damascus goats, respectively. The breed-related difference observed on the plasma disposition of IVM between Kilis and Damascus goats could be attributable to different excretion pattern or specific anatomical and/or physiological characteristics such as body fat composition of each breed.     

家畜伊维菌素中毒的研究

作者综述了伊维菌素的杀虫及中毒机理,临床应用的安全性及犬、猫、羊、兔、牛的中毒剂量、临床症状、病理变化、预防、治疗措施,并说明了阿维菌素、伊维菌素和多拉菌素的应用。认为家畜中毒的原因是超量使用该药物;除敏感犬种外,伊维菌素是当前防治畜禽寄生虫病的最佳药物之一,同时指出对发生中毒和过敏的动物,早期发现,治疗得当,则治愈率高。     

催奶灵注射液的安全性试验

通过豚鼠的全身主动过敏性试验、家兔的血管和肌肉局部刺激性以及体外溶血性试验,对催奶灵注射液进行了安全性评价。结果表明：本品对豚鼠无明显过敏性反应,静脉和肌肉注射对家兔耳缘静脉和肌肉组织无明显局部刺激,对家兔红细胞无明显体外溶血,各项安全性均较好,可推荐临床使用。